Shanghai News, June 1st (Reporter Chen Jing) May 30th every year is World Multiple Sclerosis Day, which was established by the International Multiple Sclerosis Union (MSIF) in 2009 to arouse the world’s attention to the disease. This year’s theme is "making love accessible, connecting you and me", aiming at strengthening the connection between patients with multiple sclerosis and between patients and society, and helping them gain more understanding and care.

　　In order to help more people understand Multiple sclerosis, enhance the public’s attention and reduce the burden of patients’ disease management, Professor Yan Xu, chief physician of neurology department of Peking Union Medical College Hospital, Professor Chen Xiangjun, chief physician of neurology department of Huashan Hospital affiliated to Fudan University, and Professor Qiu Wei, chief physician of neurology department of the Third Affiliated Hospital of Sun Yat-sen University, gave scientific answers on the diagnosis and treatment of multiple sclerosis.

Many symptoms are easy to be ignored, so the diagnosis of multiple sclerosis needs urgent attention.

　　Multiple sclerosis is a chronic and inflammatory demyelinating disease of central nervous system mediated by immunity. According to related research, the incidence and prevalence of multiple sclerosis are affected by geographical distribution and race. China is a low incidence area of multiple sclerosis, with an incidence rate of 0.235/100,000 people per year. At present, there are about 2.3 million patients with multiple sclerosis in the world. At the same time, multiple sclerosis is common in young adults, especially in women, and the number of patients is about three times that of men, so it is also called "beauty disease".

　　Up to now, there is no clear conclusion about the pathogenesis of multiple sclerosis, which may be related to many factors such as heredity, environment and virus infection. It is precisely because of the rarity of multiple sclerosis that the symptoms of the disease are very strange to the public in the early stage. The Survival Report of Multiple Sclerosis Patients in China, designed by Professor Yan Xu, Chief Physician of Neurology Department of Peking Union Medical College Hospital, shows that in 2019, 97% of patients with multiple sclerosis had never heard of multiple sclerosis when they were diagnosed.

　　Professor Yan Xu said: "Many patients may have symptoms in the early stage, but they didn’t realize that they had multiple sclerosis and went to the hospital. As a result, the median time from symptoms to diagnosis of multiple sclerosis in China was five years. If the patient begins to receive treatment within half a year of symptoms, the risk of entering disability in the future will be very low. "

　　Therefore, being alert to early symptoms will help the early diagnosis of multiple sclerosis. However, due to the diverse clinical manifestations of multiple sclerosis, common symptoms include decreased vision, diplopia, limb sensory disturbance, limb movement disturbance, ataxia, bladder or rectal dysfunction, etc., which also brings certain difficulties to the diagnosis.

　　Professor Chen Xiangjun, chief physician of the Department of Neurology, Huashan Hospital affiliated to Fudan University, said: "The initial symptoms of multiple sclerosis include suddenly being unable to see with eyes and feeling numb and weak on one side of the limb when walking, which is easy to be ignored. At the same time, there are some typical symptoms, such as ataxia, dizziness, unsteady walking, swaying, intonation when speaking, and involuntary eye tremor. It is also necessary to attach great importance to whether there is demyelination of the central nervous system when these symptoms appear. In addition, some symptoms are paroxysmal, such as instant headache or numbness of limbs, and uncommon symptoms such as cognitive dysfunction need to be vigilant. When these symptoms occur in young people, especially when these symptoms persist, you need to find a specialist doctor. "　

　　According to the latest data at home and abroad, the incidence and prevalence of multiple sclerosis are on the rise. In view of this phenomenon, Professor Qiu Wei, the chief physician of the Department of Neurology, the Third Affiliated Hospital of Sun Yat-sen University, explained it from three aspects: first, it may be because the prevalence and incidence of neuroimmune diseases, including other immune diseases, are increasing, which makes the prevalence and incidence of multiple sclerosis included increase; Secondly, it may come from the improvement of the diagnosis level of multiple sclerosis at home and abroad, and the support of new imaging technology and biomarkers for the diagnosis of multiple sclerosis. In addition, the public’s awareness of multiple sclerosis is also constantly improving, which makes more patients exposed, leading to an upward trend in the current incidence and prevalence data.

Make a targeted treatment plan to treat not only the "body" but also the "mind"

　　At present, multiple sclerosis can not be completely cured, but fortunately, there are already treatment programs around the world to effectively delay the progress of multiple sclerosis. In China, in recent five years, with the continuous improvement of domestic medical insurance policy and rare disease policy, more therapeutic drugs have been introduced from abroad, and the policy support for clinical treatment of patients with multiple sclerosis has been strengthened, greatly improving the accessibility of innovative drugs for multiple sclerosis in China.

　　With more and more therapeutic drugs, multiple sclerosis has gradually moved to the stage of self-medication and self-management, which makes it more important to choose a reasonable treatment plan. Only by choosing according to the course of disease, symptoms, adaptability and economic situation of different patients can patients benefit the most.

　　Professor Chen Xiangjun introduced that the treatment of patients with multiple sclerosis is divided into two stages: acute stage and chronic stage, and the treatment objectives of these two stages are different. In the treatment of acute phase, doctors need to quickly reduce the inflammatory process of immunity in vivo and reduce the damage of inflammatory process to the central nervous system as soon as possible. Chronic treatment, that is, remission treatment, is also very important. Because multiple sclerosis is a chronic disease process, it is necessary to choose appropriate disease adjustment and treatment drugs, that is, DMT (disease correction therapy) drugs.

　　"China’s emphasis on rare diseases has led to the introduction of many DMT drugs into China and is within the scope of medical insurance coverage. At present, some DMT drugs in China include common interferon beta, oral drugs, and antibody drug olfatomazumab. " Professor Qiu Wei introduced that olfatomuzumab has the characteristics of high efficiency and relative safety, at the same time, the dosage is accurate, which is beneficial to the treatment of multiple sclerosis in China to help realize the coverage and management of the whole population and the whole course.

　　Under the premise of medicine available, how to manage patients with multiple sclerosis at home has also become a common problem for doctors and patients. In the disease management of patients’ daily life, Professor Yan Xu suggested that, first of all, we should correctly establish the understanding of multiple sclerosis, not take it seriously, but not take it too seriously; Secondly, in terms of lifestyle, it is necessary to maintain the normal level of vitamin D, properly bask in the sun and supplement more dairy products; In addition, avoid smoking, control weight and keep proper exercise.

　　"In addition to paying attention to their own diseases, we also need to pay attention to the physical and mental health of patients, and finally achieve the goal of improving the quality of life of patients. Therefore, at the same time as drug treatment, symptomatic treatment is also needed. " Professor Chen Xiangjun emphasized that correct and active rehabilitation training is very beneficial to restore neurological function. Once there are obstacles in physical activity, or sensory obstacles, or obstacles in bladder and sphincter, we should actively seek correct rehabilitation treatment. Not only that, but also need to manage emotions.

Note: please be sure to indicate the source when reprinting the content of the article! 　　

Editor: Chen Jing　　

—— January 2, 2024 [CCTV] Focus interview, new deployment and new actions

February:

The People’s Bank of China, China Banking and Insurance Regulatory Commission, China issued the Measures for the Risk Classification of Financial Assets of Commercial Banks (with a reporter’s question)

March:

The People’s Bank of China held a working conference on financial stability in 2023.

April:

Important achievements have been made in preventing and resolving financial risks

The Eighth Anniversary of the Implementation of the Deposit Insurance Regulations | Six Questions and Six Answers on Deposit Insurance

eightMonth:

China People’s Bank, General Administration of Financial Supervision, China Securities Regulatory Commission jointly held a video conference on financial support for the real economy and prevention and resolution of financial risks.

November:

[Xinhua News Agency] Authoritative Interview | Insist on Serving the Real Economy and Keeping the Bottom Line of Financial Risks —— Interview with Pan Gongsheng, Governor of the People’s Bank of China and Director of the State Administration of Foreign Exchange.

[CCTV] Minister of Economic Hotspots talks about the overall controllable risks of real estate finance and local debt.

[CCTV] Authoritative Interview | Monetary Policy, Exchange Rate and Financial Risk: How Central Bank Governors Respond to Financial Hotspots

[Column] Effectively Prevent and Resolve Financial Risks and Firmly Hold the Bottom Line of No Systematic Risks.

1905 movie network news Recently, the famous director sam mendes’s new film "1917" released a brand-new preview. In the notice, two young soldiers were ordered to go through the position of bullets and deliver an important message. The time given to them by the boss is one day.

The whole preview is full of postmodern texture, and music, lens shifting and editing are not the models of family ethics drama that Mendes is good at. Moreover, the preview sequence of shots and subtitles appear in exactly the same way, which creates a closed-loop structure in vision and plot, which is very novel. The story of the film took place in World War I, 1917. Two young soldiers were appointed by their superiors to pass through the front line and enemy positions to deliver a message. This information is very important because it concerns the lives of tens of thousands of soldiers — — Including the brother of the soldier who passed the information. And the time given to them by the boss is one day. This setting of the time of day, a character and a war scene is easy to remind people of the "three unifications" in drama, and it is also easy to think of it.

The film was produced by Amperin Company in Steven Allan Spielberg. Colin firth, benedict cumberbatch, mark strong, andrew scott, richard madden, george mckay, Dean-Charles Chapman, daniel mays, Adrian Scarborough and others starred. According to the plan, the film will be released on a small scale at Christmas this year and on a large scale on January 10th next year. According to this release schedule, the film will undoubtedly enter the award season.

China women’s football missed the Paris Olympic Games: China’s football failed. China women’s football finally ranked third in the group B of the women’s Asian regional qualifiers for the Paris Olympic Games, and ended up out together with the Korean women’s football. This failure is not only the failure of women’s football in China, but also the failure of football in China.

Song Kai, the new president of China Football Association, shouted that the first goal after taking office was to ensure that China women’s football team could advance to the Paris Olympic Games, but now he can’t even qualify for the group stage, which makes people question his leadership. Song Kai strengthened the leadership team after taking office, trying to make China women’s football team stand in the world football. However, this failure made people question his leadership.

Football is a team sport that needs more professional management and more competitive players. China’s football needs to change in order to gain a foothold in the world football. The outcome has long been doomed. As early as the loss to the Korean women’s football team, the qualifying situation of the China women’s football team has been decided. Even if the China women’s football team won the Korean women’s football team, it still missed the best second place.

This defeat was a great loss of face for the players of China women’s football team, and many people didn’t even have a chance to make up for it. After the game, many women football players in China shed tears, and the girls were very unwilling to lose in the Xie Chang session of the whole team. Perhaps the lack of sufficient competitiveness has shattered the dream of China women’s football team. The Olympic Games is one of the top events in the world, and every country will send the best athletes to participate.

China women’s football team needs more time and energy to improve its own level in order to have better results. In the group match, the Uzbek women’s football team beat the Indian women’s football team 3-0, and became the second best team with 6 points and 2 goal difference, and advanced to the next stage together with the Australian women’s football team, the Korean women’s football team and the Japanese women’s football team.

Uzbekistan’s women’s football team made China’s women’s football team desperate to the end, and people had to sigh the failure of China’s women’s football team. In a word, the China women’s football team missed the Paris Olympic Games, which is the failure of China football and Song Kai. China’s football needs to be changed, with more professional management and more competitive players, in order to gain a foothold in the world football.

I hope that China Women’s Football Team can learn from this failure and make persistent efforts to achieve better results in future competitions.

In the final of the 2022 Women’s Asian Cup, after falling behind 0: 2 in the first half, Tang Jiali and Zhang Linyan scored tenaciously to equalize the score. Xiao Yuyi scored the winner in injury time. China women’s football team won 3-2, and stood on the top of Asia again after 16 years, and was crowned the ninth Asian Cup champion.

The ball is coming, beautiful! Xiao yuyi.

In 2009, Premier League Manchester United took the seat at Old Trafford, which ushered in the challenge of Manchester City, the city’s sworn enemy. This is a contest in which Tevez turns his back on his enemy and throws himself into the city, plus controversial penalties, midfield lore and other dramatic exciting elements of football. With Owen’s stoppage time goal, Manchester United beat Manchester City 4-3, and was later selected as "the best game in the Premier League in 20 years" by Premier League officials, which is far behind Manchester United today.

In the 2006 World Cup, Argentina swept Montenegro 6-0. Cambiaso, who came off the bench, took over Crespo and tapped his heel to expand his lead. You should know that this ball is a team cooperation that has been scored by a total of 24 wonderful passes, which is a classic in the history of the World Cup.

Fenerbahce and his arch-rival Besiktas met in the Turkish Cup. In the match, Van Persie had an argument with the opposing defender Tossici, and his slightly exaggerated actions led to the latter being sent off, which angered the fans at home and began to insult Van Persie. Then Van Persie scored a goal that sealed the victory for the team. After the goal, Van Persie made a provocative celebration in front of Besiktas captain Ozyakup. After the game, the Turkish Football Association suspended the two men respectively. Football name picture (28).

Source: Global Times

German "Economic Weekly" December 7 article, original title: China responded to the car tsunami in this wayChina is already the largest automobile manufacturer and exporter in the world. Nevertheless, the production capacity of BYD, Weilai, Geely and other manufacturers is too large for the domestic market. The latest satellite images show that there is a bigger plan behind it. China hopes to inject millions of cars, especially electric cars, into the global market in the next few years.

At present, the main reason why this plan is blocked is that it is difficult for China cars to be shipped abroad. Most importantly, they lack the necessary means of automobile transportation, that is, ro-ro ships. There are more than 700 such ships in the world, of which less than 100 are operated by China. According to the China Shipbuilding Industry Association, only about 10 ships are suitable for ocean transportation.

According to the Center for Strategic and International Studies (CSIS), by 2026, China Shipyard will build about 200 new ro-ro ships, 76 of which will be built for customers in China. Today, large ro-ro ships can usually accommodate 7000 to 9000 cars.

Another sign of the car tsunami can also be found in the port of China. Recently, a large area of the port has been transformed into a new car loading parking lot. This development is most obvious in the Pearl River Delta, where an island has been transformed into a large export parking lot.

Port and logistics companies are also trying to find creative ways out. For example, they use special standard containers, and three or four cars can be nested and stacked. This is not enough. COSCO Shipping Group has developed special shelves, which can stack vehicles together and transport them by ordinary bulk carriers. These ships are now transporting logs for China from Europe and transporting China cars to Europe on their return journey.

In order to overcome the bottleneck at sea, in 2022, COSCO Shipping Special Transportation established Guangzhou Yuanhai Automobile Shipping Co., Ltd. jointly with Shanghai Port Logistics and SAIC Anji Logistics to better help China automobile to enter the global market. (Author Thomas Stozel, translated by Aoki)