What is the progress of BCMA target development? Which biotech will win?

foreword

Malignant multiple myeloma(multiple myeloma ; MM) is a kind ofwithMalignant disease characterized by massive proliferation of monoclonal plasma cells in bone marrow. B cell maturation antigen (BCMA) is highly expressed on the surface of MM cells. In the past few years, great progress has been made in various BCMA targeted immunotherapy for recurrent/refractory MM patients, including anti-BCMA monoclonal antibodies, antibody-drug conjugates (ADC), bispecific T cell binders (BITE) and chimeric antigen receptor adoptive T cell therapy (CAR-T). The 63rd annual meeting of American Hematology Society updated some information about the application of BCMA in MM, and based on this annual meeting, the related contents of this paper were sorted out [1].

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Immunotherapy targeting BCMA: (1)ADC;   (2)CAR-T;   (3)BiTE; 

copywriter | NING

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BCell maturation antigen (BCMA)

Also known as TNFRSF17, it is a member of TNF-receptor family, and is called tumor necrosis factor receptor superfamily 17. This receptor is expressed on the surface of B lymphocytes and plasma cells, and is a marker protein of B lymphocyte maturation. Under physiological conditions, BCMA is mainly expressed in plasma mother cells and terminally differentiated plasma cells (PC). Under pathological conditions,BCMA Almost in all MM Tumor cell line (80%–100%) are expressed.The number of BCMA on the surface of malignant PC is much higher than that of conventional PC, which explains why BCMA target has become a battleground for major biological enterprises.

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Monoclonal antibody targeting BCMA

SEA-BCMAIt is a new humanized non-fucosylation. IgG1 mAb. The working mechanism of SEA-BCMA may include blocking BCMA activation and its downstream proliferation signal pathway, regulating antibody-dependent cell phagocytosis and enhancing antibody-dependent cytotoxicity.

Its clinical phase I trial (SGNBCMA-001; The preliminary results of NCT03582033) show that it has good safety and combination potential: SEA-BCMA also shows encouraging treatment duration and initial anti-tumor activity in the advanced R/R MM population who have received a lot of treatment before.

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Source: blood (2021) 138 (Supplement1): 2740.doi: 10.1182/blood-2021-146047.

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Bispecific T Cell cement (BITE)

BiTEs can simultaneously target BCMA on MM tumor cells and CD3ε domain of TCR on T cells. After T cells are combined with myeloma cells, cytotoxic T cells can be activated and secrete cytotoxic factors, thus producing cell killing effect.This part is still in Ⅰ at present./Phase ii.

The following table summarizes the clinical data of bispecific antibodies against BCMA, among which the BiTE bispecific type of BCMA×CD3 is the most common.

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Novel trispecific antibody drugs

Researchers are no longer satisfied with treating patients with R/R MM through dual-target therapy.HPN217, an extended half-life (median serum half-life:74 Hours) three specificity. T Cell activation construct (TriTAC)It simultaneously targets BCMA and CD3ε (redirected T cells), and adds serum albumin to prolong the half-life, which can exert cytotoxic effect on myeloma cells.Currently working onR/R MM of 1 /2 Phase I clinical trial for evaluation (NCT04184050). Here are some preclinical data.

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Legend: HPN217 mediates the killing effect of autologous T cells of NCG mice on BCMA-dependent/primary MM cells.

Source: blood (2021) 138 (Supplement1): 1185.doi: 10.1182/blood-2021-151880.

CDR101(CDR-lifeCompany’s products)Is simultaneous targeting.CD3BCMAandPD-L1The trispecific antibody,T cells can be induced into tumor cells expressing BCMA, and the immunosuppressive effect caused by the interaction between PD-L1 and PD-1 can be blocked at the immune synaptic site. Compared with BCMA × CD3 bispecific drugs, CDR101 leads to at least a tenfold increase in T cell-mediated tumor cell lysis, and performs better than the combination of PD-L1 inhibitor and BCMA × CD3 bispecific drugs.CDR101 It may become a new ready-made treatment, providing a more lasting response and a higher cure rate. CDR101 Has excellent drug-like characteristics, high stability and high stability.CHOHigh yield of expression.Based on these findings, new trispecific immunotherapy drugs have high clinical potential and promising clinical application [2].

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Antibody drug conjugate (ADC)

After recognizing BCMA on the cell surface, ADC internalizes it into myeloma cells. Through the degradation of lysosomes or endosomes, the payload is released, causing cytotoxicity.

Belantamab mafodotin (GSK2857916)Is targeted by humanization.BCMA IgG1 andMMAF(tubulin polymerization inhibitor). Belantamab mafodotin was approved by the US Food and Drug Administration (FDA) in 2020 to treat patients with R/R MM.This is the first target approved for listing.BCMAimmunotherapy,A multicenter phase II clinical study (NCT03525678) confirmed that the recommended regimen for patients was 2.5 mg/kg, once every three weeks, but the toxicity of the drug was mainly manifested in thrombocytopenia and pericorneal lesions, such as microcystic epithelial changes or superficial punctate keratopathy. In addition to belantamab mafodotin, several other ADCs targeting BCMA, such as AMG 224, MEDI2228 and HDP-101, have also conducted many preclinical or clinical studies at different stages.

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Legend: Incidence rate of adverse events caused by Belantamab mafodotin at 2.5 mg/kg and Q3W.

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Antibody drug conjugate (ADC) joint test.

In the joint experiment, there are two schemes: belantamab+DEX (dexamethasone) and belantamab+DEX+POM.

belantamab(2.5 mg/kg Q3W) and DEX(20-40 mg Q1W,threeCycle) jointAfter use, the objective remission rate (ORR) was 46%, the complete remission rate (CR) was 14%, the median progression-free survival (PFS) was 4.9 months, and the median overall survival (OS) was 7.4 months. The incidence of AEs from high to low is anemia (83%), keratopathy (82%; Gr3/4: 56%), thrombocytopenia (70%) and so on.

belantamab+DEX+POMUnion ofIn the experimental scheme, the ORR was 88.9%(48/54), and the CR and PR rates were 24.1%(13/54) and 20.4%( 11/54) respectively. However, keratopathy (96.9%) was also the most common AE, and 56.7% of such patients had reached Gr 3/4. These two studies show that POM and DEX may have a positive effect on the curative effect of belantamab. howeverKeratosis is still a challenge in the treatment process.

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Legend: Detailed rules and results of belantamab+DEX (Dexamethasone) joint trial scheme.

Source: Blood 2021; 138 (Supplement 1): 1642. doi: https://doi.org/10.1182/blood-2021-149791

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CAR-Ttherapy

nowTwo CAR-T therapies based on BCMA have been approved for marketing.And is used for treating patients with multiple myeloma.

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Source: "CAR-T therapy targeting BCMA"

7.1

Cilta-cel (Carvykti) for Orense injection.

Sidaki Orense injection(Cilta-cel,Carvykti) yes2022year2moon28Listed in China (NMPAApproved for listing/FDAFormal approval) targeting.BCMAofCAR-TCell products, jointly developed by Janssen and Legendary Bio, Legendary Bio owns 70% interests in Carvykti Greater China and 50% interests overseas.

In CARTITUDE-1 trial, the overall remission rate was 97%, the 18-month progression-free survival rate was 66%, and the 2-year progression-free survival rate was 61%. The 18-month overall survival rate is 81%, and the 2-year overall survival rate is 74%. Compared with similar products, this data is very gratifying. According to the latest news from Kingsley, the sales of the legendary BCMA CAR-T new drug Carvykti in the first half of the year was 24 million US dollars.

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7.2

Abecma(Ide-cel)

2021yearthreemoon26Day,FDAapproveBaishimei SquibbAbecma(Ide-cel)be listedAbecma is also a BCMA-oriented CAR-T cell therapy, which is customized from patients’ autologous T cells. Clinical data show that the overall remission rate of all patients is 72%, of which the complete remission rate is 28%; Even for patients who have received various regimens, the remission rate of Abecma still reaches 72%, and this remission is very lasting, and 65% of patients are over 12 months.

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Legend: preparation principle of Abecma

7.3

Iqalunsei injection

In addition, June 2, 2022Reindeer biology/Xinda biologyAnnounce BCMA CAR-T therapyIqalunsei injectionThe listing application was obtained.NMPAAccepted, it is expected to become the first domestic independent research and development of the whole process.CAR-Ttherapy. The clinical research data reported at the 63rd ASH annual meeting in 2021 showed that the overall remission rate (ORR) was 94.9%, and the complete remission rate/strict complete remission rate (CR/sCR) was 58.2%, showing the excellent safety and effectiveness of Iqalunsei injection.

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Source: NMPA official website

7.4

The clinical trial of CAR-T therapy targeting BCMA is as follows

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summary

Judging from the listing situation,Belantamab mafodotin (GSK2857916) is composed of humanized targeting BCMA IgG1 and MMAF (tubulin polymerization inhibitor), which is the first targeted BCMA immunotherapy approved for marketing. At present, there are two CAR-T therapies that have been put on the market, developed by Bristol-Myers Squibb respectively.Abecma(Ide-cel), developed in cooperation with Janssen)/ Legendary Biology.Sidaki Orense injectionFrom the data point of view, the latter effect is better, the ORR is increased from 72% to 97%, and other indicators are relatively better. On June 2nd, 2022, Reindeer Bio/Cinda Bio announced BCMA CAR-T therapy.Application for marketing of Iqalunsei injectionIt has also been accepted by NMPA, and it is expected to become the first CAR-T therapy independently developed in the whole process in China. Let us wait and see! From the therapeutic point of view, CAR-T therapy is at the forefront in terms of clinical data and market situation, but we can’t simply judge the advantages and disadvantages of these products. For example, better anti-BCMA CAR-T cell therapy requires more complicated preparation conditions and more expensive treatment costs, which are unbearable for ordinary families. Therefore, while continuing the existing research, it is necessary to study the potential mechanism affecting the curative effect in order to optimize BCMA targeted immunotherapy.

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Legend: Comparison of clinical efficacy between different immunotherapy products targeting BCMA (see [1] for specific clinical data).

reference data

[1]Targeting BCMA to Treat Multiple Myeloma: Updates From the 2021 ASH Annual Meeting. Front Immunol. 2022 Mar 7; 13:839097. doi: 10.3389/fimmu.2022.839097. PMID: 35320942; PMCID: PMC8936073.

[2] Blood 2021; 138 (Supplement 1): 1583. doi: https://doi.org/10.1182/blood-2021-152160

[3] Blood 2021; 138 (Supplement 1): 1642. doi: https://doi.org/10.1182/blood-2021-149791

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BYD was investigated by two institutions: BYD actively deployed its overseas business and entered the passenger car market in Australia, Colombia, Brazil, Singapore, Costa Rica, Thailand and other cou

  () The Record Form of Investor Relations Activities was released on April 12, and the company was investigated by two institutions on April 11, 2023. The types of institutions are other securities companies. The main contents of investor relations activities are introduced:

  Q: What was the sales volume of BYD and Tengshi brand in March?

  A: BYD sold 207,080 vehicles in March 2023, including 206,089 passenger cars, up 97.5% year-on-year; There are 13,312 passenger cars exported. BYD Tengshi D9 ranked first in the "Sales List of New Energy Luxury MPVs with an average transaction price of 415,000" for three consecutive months with a score of 10,398 units (up 42% from the previous month), and continued to consolidate its position as a "new benchmark for the value of new energy luxury MPVs in China".

  Q: What’s the feedback from BYD Seals?

  A: Since its listing, BYD Seal has become an explosive model in the sports market with its excellent quality and leading strength. As the world’s first production car equipped with CTB battery body integration technology, Seal is not only BYD’s practical exploration of the next generation of electric vehicles, but also the realization of its innovative technology in products, and it is also BYD’s masterpiece in the advanced technology field of electric vehicles. On April 7th, CCTV’s third "China Automobile Fengyun Festival" came to a perfect conclusion, and BYD seal, a marine leopard, won the highest prize "Jury Award" and became the biggest winner of this "Festival". This award is not only a high recognition of BYD Seals, but also an authoritative hardcore endorsement comparable to the purchase guide.

  Q: What is the overseas response of BYD models?

  A: BYD has actively deployed its overseas business, and has successively entered the passenger car market in Australia, Colombia, Brazil, Singapore, Costa Rica, Thailand and other countries, which has been widely concerned and loved by local consumers. Recently, Thailand AutoLife official website data shows that in March, the number of BYD ATTO3 cards reached 2,434, winning the title of pure electric vehicles in Thailand for the third time in a row. In the first quarter, the number of BYD ATTO3 licenses was 5,542, accounting for 37.5% of the total number of pure electric vehicles in the first quarter, and it continued to lead the pure electric passenger car market in Thailand.

  Q: Please introduce BYD’s design concept?

  A: Since Wangwang brand appeared, its subversive core technology has been widely concerned, and the discussion has always been hot. At the same time, highly recognizable product design has also received great attention. Looking up at the car design inspiration comes from the universe, which is a space that contains infinite time, energy and emotion. The place leading to this space is called "dimension door", which is the most recognizable part of looking up to the brand-new family visual identity of the car, hoping to bring a brand-new visual experience to users. Looking up at the front face design of U8 is the most recognizable part of modeling. Dimension door’s family-style design language is integrated. A large area of front and rear lighting design creates a visually full sense of volume. Headlight lines outline the image of dimension door, presenting the ultimate sense of science and technology and futurity. Driving outdoors in the wilderness and in urban traffic shows its recognition. The local light-emitting unit follows the lattice air intake grille, and the diamond light particles are regularly arranged, which changes the gorgeous lighting effects in the scenes of unlocking and welcoming guests, so that every departure is full of ritual.

  Q: Please introduce the highlights of BYD’s cloud technology?

  A: On April 10th, BYD released a new energy-specific intelligent body control system-Yunqi. The intelligent body control system of Yunqi is developed by BYD, which also indicates that BYD has become a China automobile enterprise that can independently master the intelligent body control system. The product matrix of Yunqi includes Yunqi -C, Yunqi -A, Yunqi -P and other products, which will greatly enhance the driving experience of consumers from the dimensions of comfort, control, safety and off-road. Yunbi can effectively restrain the change of body posture, greatly reduce the risk of vehicle rollover and reduce the sitting displacement of drivers and passengers. At the same time, the cloud chariot system can effectively protect the car body under complex road conditions such as snow, mud and water, avoid the collision damage of the whole car caused by terrain, improve driving comfort and safety, and realize the double protection of people and cars; BYD Co., Ltd. is mainly engaged in automobile business, mobile phone parts and assembly business, rechargeable battery and photovoltaic business, including new energy vehicles and traditional fuel vehicles, and actively expands the business field of urban rail transit. The company’s main products are rechargeable batteries and photovoltaics, mobile phone components and assembly, automobiles and related products. BYD’s leading position in the global new energy vehicle field. In 2019, BYD’s new energy vehicle product structure was further improved, and its sales volume still ranked among the top in the world.

  Details of participating institutions are as follows:

Name of participating unit Category of participating units Name of participants Guoxin Securities securities company — individual other Yu Xiaofei

McDonald’s, which has been in China for 37 years, has just been sold to China people! Will hamburgers be authentic in the future?

McDonald’s and KFC are believed to be the memories of a generation of Chinese people.

Fund Jun remembers that when he first ate it, he traveled to Shenzhen as a child. At the first meal, he clamored for McDonald’s, because he had long yearned for it in front of the overwhelming TV advertisements at that time.

There is a joke that says: the first English letter learned by kindergartens or primary school students was basically not A, but M, the M of McDonald’s.

After the reform and opening up, McDonald’s is one of the first two "foreign fast food" from the United States to enter the China market. After more than 30 years in China, I finally sold China’s business to China people.

(The first McDonald’s restaurant in mainland China at the east gate of Shenzhen)

Let’s take a look at the opening of the first McDonald’s in China.

On October 8, 1990, the first McDonald’s restaurant in mainland China — — Guanghua Restaurant was grandly opened in Dongmen Commercial Pedestrian Street, Luohu District, Shenzhen.

The queue for buying fast food went from the third floor to the first floor of the restaurant, and then turned around the whole Guanghua several times. Many people from Shenzhen went to taste McDonald’s food with their families. The customers who came to watch the grand opening of McDonald’s restaurant packed more than half of Dongmen Commercial Street.

The number of employees serving the opening of the new restaurant is nearly 1000. In addition to the first batch of more than 400 employees in China, McDonald’s temporarily transferred more than 500 employees from the Hong Kong company to help.

Guanghua restaurant at that time could be settled in Hong Kong dollars or RMB. Unexpectedly, the front of the Hong Kong dollar settlement counter was crowded with Shenzhen people who were born and raised in Shenzhen. It is said that in order to come to McDonald’s to taste the fast food chain, they all prepared a sufficient amount of Hong Kong dollars in advance.

Yes, McDonald’s in China changed its name from "foreign" to "Chinese".

On August 4th, CITIC Hong Kong Stock Exchange announced that the acquisition of the controlling interest in McDonald’s business in China Mainland and Hong Kong was completed on July 31st. This will become the largest McDonald’s franchise business outside the United States, and the partners will operate and manage about 2,700 McDonald’s restaurants in China Mainland and Hongkong market.

CITIC announced on January 9th this year that CITIC, CITIC Capital Holdings, Carlyle Investment Group and McDonald’s, a subsidiary of CITIC Group, jointly announced that they had reached a strategic cooperation and established a new company. The new company will acquire McDonald’s business in mainland China and Hong Kong for a total consideration of up to US$ 2.08 billion (about HK$ 16.14 billion).

After the transaction is completed, CITIC and CITIC Capital will hold a total of 52% of the controlling shares in the new company, while Carlyle and McDonald’s will hold 28% and 20% respectively.

CITIC Group has a total of 176 companies with total assets of 2.1 trillion yuan, and its business involves finance, resources and energy, manufacturing, engineering contracting, real estate and other fields. In recent years, CITIC Group has also begun to lay out the consumption field. Just before the acquisition of McDonald’s China, Chunxin Capital, a subsidiary of CITIC Group, acquired 100% equity of Jianlibao Trade in the hands of Uni-President Group for 950 million yuan.

Quite simply, the good times in China market are gone.

Think about it, will you go to McDonald’s and KFC every day to solve the problem of eating?

The data shows that the market share of KFC and McDonald’s in China’s fast food industry has dropped from about 57% (40% and 17% for two brands respectively) to about 37% (24% and 13% for two brands respectively).

Unable to maintain high growth, the trick McDonald’s came up with to get out of the predicament is to sell its brand management rights in the China market for the next 20 years, including the management rights of 2,200 stores that are operating.

Both companies have obtained a lot of funds for this round of transactions, which will be an important source of their next investment from me. Both companies have a large number of restaurants waiting to be renovated — — No matter what kind of restaurant, young people want a more comfortable and fashionable dining environment. In order to find consumers in the fragmented market, they have to catch up with the trend of digitalization. These all need money, a lot of money.

Fund Jun did a search in Weibo. This kind of problem actually appeared.

Many netizens are asking:

Are there any cups, toilet paper, free wifi, ketchup and straws available for free?

You can’t get ketchup after that.

I just want to ask, when boycotting American goods in the future, should McDonald’s boycott [allow sorrow]

Can I go to McDonald’s to go to the bathroom in the future?

These strange questions can only be observed later.

Today, Fund Jun continued to talk about the development of overseas brands after Chinese capital acquired them.

On May 21st, 2012, Wanda announced the acquisition of AMC, the second largest cinema in the world, for US$ 2.6 billion. This is the first international merger of China’s cultural industry and Wanda’s total transaction amount is 2.6 billion US dollars, including buying 100% equity and taking on debt. According to the M&A agreement, after the completion of the merger, Wanda Group will take over 338 cinemas under AMC and operate AMC as its wholly-owned subsidiary, and at the same time inject no more than 500 million US dollars into it every year.

A masterpiece of Wanda’s overseas mergers and acquisitions is now caught in the dilemma of loss-making and layoffs. On August 2nd, AMC Entertainment Holding Company (hereinafter referred to as "AMC"), a subsidiary of Wanda Group, released its second-quarter performance forecast, with estimated revenue ranging from $1.2 billion to $1.204 billion, net loss ranging from $174.5 million to $178.5 million, and loss per share ranging from $134 to $1.36, compared with earnings per share of 24 cents in the same period last year. In the face of performance losses, AMC also indicated that it will cut costs through measures such as layoffs. However, under the situation that the global film market is relatively depressed, AMC faces greater challenges. For Wanda Group, the frequent performance difficulties of overseas assets are not conducive to the layout of Wanda Group’s global film and television industry.

In 2004, under the auspices of Yang Yuanqing, Lenovo acquired IBM’s PC business for a total price of 1.25 billion US dollars. This acquisition, which Lenovo called "snake swallowing elephant", made Lenovo become the third largest computer manufacturer in the world.

After the acquisition, Lenovo experienced a long run-in because of cultural conflicts and changes in management. Until 2008, Lenovo lost $226 million, and Lenovo CEO was changed from Amelio, who was originally from IBM, to Yang Yuanqing.

In the 12 months to the end of March 2017, Lenovo’s total revenue was $43 billion, a year-on-year decrease of 4%. It made a net profit of $535 million, but nearly 85% of it came from the income from selling houses in the past year. Other products, including personal computers, mobile phones and servers, contributed less than $100 million in profits.

In the past fiscal year, Lenovo’s PC business was not very good, facing the global environment of the fifth consecutive year of decline in shipments. And, although Lenovo’s market share as of the end of 2016 is still the first in the world, reaching 21.7%, the second-ranked HP has narrowed the gap from 1.8% to 1.3%. An important reason for the overall market search is that people don’t change computers as frequently as before: once in the past 3-4 years, now 5-6 years.

In October 2014, Lenovo Group acquired Motorola Mobility, with a total acquisition of about 2.91 billion US dollars, and Lenovo immediately became the third largest smartphone manufacturer in the world.

After the acquisition, nearly 3,500 employees from all over the world will join Lenovo, including about 2,800 employees in the United States.

Lenovo will adopt a dual-brand strategy, that is, the parallel strategy of MOTO and Lenovo. Moto will be a supplement to Lenovo’s high-end product line in China, and its product design, R&D and operation are completely independent.

Looking back at Lenovo Mobile’s strategy, it is widely believed that Lenovo failed to grasp the transformation of Internet mobile phones or the offline channel changes initiated by OPPO and vivo.

In terms of mobile business, the revenue of Lenovo’s mobile business group since 2014 decreased by 10% year-on-year to US$ 7.707 billion. Revenue outside the China market fell by 5.4%, and profit margin before tax fell by 1.9%. At the beginning of 2014, Lenovo still had the status of the second smartphone manufacturer in China, but in the past three years, its ranking dropped to ten, and it was overtaken by Huawei, Xiaomi, OPPO, vivo and other mobile phones.

On the morning of January 12th, 2016, the signing ceremony of Wanda Culture Group’s acquisition of American Legendary Pictures Company was officially held in Beijing. Wanda Group will acquire 100% of Legendary Pictures, a well-known Hollywood film and television production company in the United States, with a cash of no more than US$ 3.5 billion (about RMB 23 billion), which is also the largest cultural acquisition of China enterprises overseas. Thomas Tull, Chairman and CEO of Legendary Pictures, will remain in office and continue to be responsible for the day-to-day operation of the company.

One year after Wanda acquired Legendary Pictures, ThomasTull, founder, chairman and CEO of Legendary Pictures, announced his resignation.

On January 17, 2017, the American media "Hollywood Reporter" reported that Thomas Tour’s resignation was not voluntary, but was under pressure from Wanda. Wanda is dissatisfied with his management level and ability to operate the Great Wall, Pacific Rim 2 and other projects.

On January 19th, Dalian Wanda Group Co., Ltd. issued a statement saying that online media reported recently that Thomas, the legendary American CEO, resigned because of the failure of Great Wall. The report is unverified and seriously inaccurate.

On August 2, 2010, Geely Holding Group officially completed the acquisition of all the shares of Volvo Car Company, a subsidiary of Ford Motor Company.

When negotiating the acquisition of Volvo, Li Shufu met with Volvo engineers. The other party made a somewhat harsh request, asking him to explain in three words why Geely’s acquisition of Volvo is the best. The scene was a little tense, and the host tried to beat the circle. Li Shufu stopped him: no problem, I can answer, three words, very good, because, "IloveYou!" "

Seven years after Geely acquired Volvo’s passenger car business, the two sides plan to jointly enter the mid-to-high-end automobile market in the form of a joint venture.

On August 4th, Link Investment Co., Ltd. was established in Ningbo, Zhejiang. This is a three-party joint venture, with Geely Automobile Holdings Limited, Zhejiang Geely Holding Group and Volvo Car Group holding 50%, 20% and 30% respectively.

Many market participants are optimistic about the cooperation between Geely Automobile and Volvo. Ni Wei, an analyst at Everbright Securities, said in the research report that they are optimistic about the long-term cooperation between Geely and Volvo based on Lectra. "The company or its own brand will switch up one of the most certain targets." The research report predicts that the sales volume of the Lectra brand will reach 15,000, 150,000 and 300,000 respectively from 2017 to 2019.

In 2016, Haier Group announced on January 15th that it would acquire the home appliance business of General Electric (GE). The acquisition amount is $5.4 billion, which will take over the personnel of GE’s home appliance department and its business base in the United States. At the same time, it will also obtain intellectual property rights and "GE" brand, which will be used as a foothold for officially opening up developed countries such as Europe and America. GE and Haier also announced that they will establish a long-term strategic partnership and explore cooperation in industrial internet, medical care and advanced manufacturing.

On the evening of March 30, 2016, Midea Group announced that Midea intends to acquire 80.1% equity of Toshiba’s white goods business with its own funds of about US$ 473 million after negotiation between the two parties. With this transaction, Midea will receive 40 years of global authorization from Toshiba brand, more than 5,000 patents related to household appliances, and the markets, channels and manufacturing bases of Toshiba household appliances in Japan, China and Southeast Asia. However, Midea’s acquisition needs to undertake about $220 million in debt from Toshiba’s home appliances.

TCL Group, one of the pioneers in the field of household appliances in China, and Thomson Company, the fourth largest consumer electronics supplier in the world, formally signed an agreement in Guangzhou to reorganize their color TV and DVD businesses and form the largest color TV supplier in the world — — — TCL— Thomson electronics company. This is also the first time that China’s home appliance enterprises have merged the mainstream business of the world’s top 500 companies.

The total assets of the merger and reorganization of the two parties will exceed 450 million euros. TCL International Holdings will become the major shareholder of the joint venture company, accounting for 67% of the shares, while Thomson will hold the remaining 33%. The newly established joint venture company has more than a dozen production bases in Europe, America and Asia, with an annual sales of 18 million color TV sets, making it the largest color TV supplier in the world.

On June 21, 2016, Tencent announced that it had acquired 84.3% equity of Supercell after consulting with Finnish mobile game developer Supercell84.3% The transaction amount is expected to be 8.6 billion US dollars (about 56.6 billion yuan). Supercell is a game giant from Finland. As of March 2016, the number of daily active users (DAU) of its games has exceeded 100 million.

According to sources, any buyer of Supercell must agree to the condition that six founders control the company. The new owner can’t force an IPO or fire the existing management team. At present, Supercell has launched games such as Clash of Tribes, Cartoon Farm and Raiders of the Island for the global market. In contrast, Zynga, which has more mobile game products, has about 21 million daily active users, while Gameloft and Glu have about 19 million and 5 million respectively. King, the developer of Candy Legend, has more than 130 million daily active users. Among them, the "local tyrant game" and "clash royale", which are well known by netizens, were also developed by them.

Source: China Fund News (ID: China Fund News)

Reporter: Taylor

100,000-class domestically produced cars that dare to challenge joint ventures, BYD Qin PLUS DM-i or Geely Xingrui, who is more valuable?

Self-owned brand SUV models have already laid their own world. However, it is still difficult for domestic independent brands to compete with joint venture models in the family car market, but with the strength of independent brands, this situation has gradually changed. High-quality models such as BYD Qin PLUS DM-i and Geely Xingrui also have the ability to compete with joint venture models at the same level. What are the emphases of these two excellent cars? The following analysis one by one:

Byd Qin PLUS DM-i and Geely xingrui,The price is in the range of 100,000-150,000, but their positioning is not the same.. BYD Qin PLUS DM-i aims at the hybrid field of Shuangtian in Japan, and its opponents include the dual engines of Ralink and Corolla, as well as the sharp mix of Lingpai and Xiangyu. And Geely Xingrui will have a wider scope of attack, directly targeting the compact family car market, and using its superb car-making technology and luxury configuration to compete for market share.

Since both of them are located in compact family cars, space is definitely a hard indicator. In terms of measurements, the length, width and height of BYD Qin PLUS DM-i are respectively4765/1837/1495mm, with a wheelbase of 2718 mm., and Geely Xingrui’s length, width and height are respectively4785/1869/1469mm, with a wheelbase of 2800 mm., is a large family car.

From the perspective of design, the advantages of independent brands in recent years are also very obvious. BYD Qin PLUS DM-i inherits the family-style design style. Although it is the lowest model of the dynasty series, its design concept is very avant-garde. The family design language of Dragon Face embodies the charm of the dragon to the fullest. The design of Geely Xingrui’s straight waterfall net also inherits the design language of Geely family, and its wider body shape and stable lines show its atmosphere and fashion.Although the appearance is radish and cabbage, each has his own love, but in terms of their design style and skill, they definitely don’t lose the joint venture model.

In terms of interiors,Both of them adopt the design of LCD instrument+floating screen.,It’s just the rotating central control screen of BYD Qin PLUS DM-i, which is more cool and practical.. However, in terms of workmanship and materials, Geely Xingrui is more luxurious and kind. Soft plastic-lined materials and leather packages can be seen everywhere, and great efforts have been made to create a luxurious atmosphere in the interior. Therefore, the interior of Geely Xingrui is also a big killer for it to challenge the joint venture car at the same level.

At the configuration level, independent brands also have great advantages.BYD Qin PLUS DM-i and Geely Xingrui are equipped with the popular L2 driver assistance system.. At the same time, compared with the two top models, Geely Xingrui has more abundant configurations, such as automatic parking, panoramic sunroof, inductive tailgate, HUD head-up display system, ventilated and heated memory seat, boss key, 10 BOSE speakers, rainfall sensor and air conditioner, all of which are more luxurious configurations than Qin Plus DM-I. It can be fully seen that Geely Xingrui has reflected the higher cost in comfortable configuration and air purification device.

In terms of power, it is also the biggest difference between the two. They all come up with powerful power units of this level in their respective fields of expertise.BYD Qin PLUS DM-i adopts a set of hybrid power system mainly driven by motor.Moreover, it is a plug-in hybrid mode. Under the battery capacity of 8.32 kWh and 18.32 kWh, it can achieve pure battery life of 55km and 120 km. It is worth mentioning that even in the case of complete power loss, driving it as a HEV-like model, its fuel consumption is very close to that of Shuangtian’s hybrid model.

Not only that,It has two versions, big battery and small battery, which can reach the ultra-long cruising range of nearly 900 km and 1200 km under the condition of full oil and full charge., is definitely the most at the same level. It is a "sweet and salty" powertrain. At the same time, in terms of power output, the large and small battery versions of BYD Qin PLUS DM-i have output power of 132kW and 145 kW respectively, and the maximum torque is 316 Nm and 325 Nm respectively. With such strong power, its 100-kilometer acceleration is only 7.9s and 7.3s s. It can be imagined that BYD’s DM-i hybrid system is by no means a hollow reputation.

Geely Xingrui’s power system is also excellent. In the price range of 100,000 to 150,000, if you want to buy a 2.0T car, it is simply rare.Moreover, this 2.0T engine is the power unit of Volvo T4, which has a maximum power of 140 kW and a maximum torque of 300 Nm.Such a high-standard power output is also the leader of this level.

But on the other hand, fuel consumption,Geely xingrui 2.0T gasoline engine is obviously not more economical than BYD Qin PLUS DM-i with hybrid system.It can also be seen that Qin PLUS DM-i spent the cost on a complex and high-tech hybrid system. The cost of Geely Xingrui is spent on high-grade working materials and luxurious and comfortable configuration.

In terms of chassis, there is also a big difference between the two.BYD Qin PLUS DM-i adopts front McPherson and rear trailing arm torsion beam suspension system, and the rear axle adopts semi-independent suspension layout.Obviously, in order to save costs, we pay more attention to the creation of space in the car and the trunk, but this setting has also made some sacrifices for maneuverability. butGeely Xingrui adopts front McPherson and rear multi-link four-wheel independent suspension.This kind of structure is the layout that a high-end car should have, and its natural excellent structure makes its training very balanced. However, in terms of vehicle positioning, Geely Xingrui prefers home use, so the suspension setting is relatively soft and comfortable, which is also in line with its comfortable home style.

In terms of vehicle warranty,BYD Qin PLUS DM-i has a 6-year and 150,000-vehicle warranty.And it uses a blade battery,It also provides the battery with a lifetime warranty of unlimited mileage and unlimited years for the first owner.There is basically no worries in use. And Geely xingruiUpgrade to a four-year 100,000-kilometer vehicle warranty under the mandatory three-year 100,000-kilometer warranty.It also highlights the principle of domestic brand service first.

In the end, by comparison, the price of BYD Qin PLUS DM-i 14.98 and Geely Xingrui 149,700 are only different from 100 yuan.In the case of similar guide prices, BYD Qin PLUS DM-i has a greater advantage.As a plug-in hybrid model, it can be exempted from purchase tax at present, so the landing price of BYD Qin PLUS DM-i can save nearly 13,000 yuan in purchase tax compared with Geely Xingrui. At the same time, its ultra-low power consumption and ultra-long warranty also reduce the burden on consumers’ subsequent car maintenance costs.

In the case that both cars can compete with the joint venture models, should we choose BYD Qin PLUS DM-i, which is energy-saving, environmental-friendly, lower in use cost and closer to pure electric vehicles, or choose Geely Xingyue, which is more calm and solemn, more luxurious and more spacious and comfortable? Then it’s up to you to make a decision.

-40℃ extreme cold test, look up to U8 three electricity, intelligence to show extraordinary strength.

Recently, a head media launched a winter test in Mohe. In the extremely cold weather of -40℃, more than 50 new energy vehicles competed on the same stage, and the actual measurement was carried out around the core dimensions that users paid attention to, such as battery life, charging power, control and intelligence. Looking at the major lists, the million-level new energy hardcore cross-country looked up to U8 with excellent results and won six first places in one fell swoop. Among them, in the field of plug-in/extended-range vehicle segmentation, Wangwang U8 Deluxe Edition successfully won the pure electric endurance achievement rate, the maximum charging power and the average charging power TOP1, and it was ranked in the first echelon in the elk test on the open road and the static fake car test by ACC in the snow at night, and also got TOP1 in the voice interaction test of winter scenes.

Leading the three power systems, looking up to U8 has more hard-core cloud-P.

This winter test was carried out in the environment of -40℃, which put forward an extreme test for the test vehicle. Before all the tests, the participating vehicles should implement the uniform maintenance standard and strictly implement the same test conditions, so as to ensure the fairness of the test and truly simulate the user’s car use situation in winter. Under the harsh test conditions, Wangwang U8 first demonstrated the leading technical level of Sandian, and stood out from the crowd to obtain excellent measured results.

From a technical point of view, looking up to U8 depends on the blade battery first. Looking up to U8, it is equipped with the easy Sifang technology platform. Four motors form the core drive source, and each wheel is controlled by one motor. On this basis, it is equipped with a blade battery whose battery core is further upgraded to meet the ultra-high charge-discharge rate requirements of the Sifang system. Compared with the previous generation blade battery, it is expected that the blade battery can reach the original specific power of 220%, and the energy density of the battery is increased by 8%. Under the condition of not increasing the volume of the central battery pack, the existing battery pack can store more energy. At the same time, the blade battery equipped with U8 also supports up to 110kW DC fast charging, and it takes only 18 minutes to charge from 30% to 80% at the earliest, so that users can effectively avoid charging anxiety, and can quickly replenish power in a short time and improve the convenience of car use.

In the end, according to the measured results, the achievement rate of pure electric endurance of U8 in ultra-low temperature extreme environment still reached 58.6%, ranking first among all plug-in/extended-range models, which performed quite well. Moreover, in the test of 180W charging pile, its maximum charging power reaches 82.33kW, and its average charging power can also reach 57.41kW, which also ranks first among plug-in/extended-range vehicles.

In addition to the hard-core three-electric system, Wangwang U8 is also equipped with Yunqi -P intelligent hydraulic body control system. The system uses five dimensions of intelligent exploration, deep collaborative intelligent calculation of software and hardware, and intelligent control of three directions and six degrees of freedom to get through the whole link of perception, decision-making and execution, which can realize all-round intelligent control of the car body and comprehensively improve the maneuverability and comfort of looking up at U8. Coming to the ice and snow trial site in Mohe, Yunqi -P showed its ultimate strength. In the off-road elk test at 50km/h, the posture of U8 body is stable and controllable, and the safety and handling are fully guaranteed, and finally the G excellent rating is obtained.

Outstanding intelligent strength, looking up to U8 voice intelligent driving double first.

Another highlight of this media winter test is to test the reliability of vehicle intelligent system in low temperature environment. In the aspect of intelligent interaction, the media specially measured the voice interaction ability of winter scenes, and issued 30 voice commands in Mandarin, including 15 common commands, 5 fuzzy commands, 4 complex commands, 3 visible-to-talk commands and 3 wakeup-free commands. After testing, Wangwang Link intelligent human-computer interaction on U8 is outstanding, and the number of successful voice commands ranks first in the audience. Functionally, U8 supports continuous dialogue in the whole scene, and users can set the duration of continuous dialogue for 20s/60s/90s, and a wake-up call can continuously issue multiple instructions such as setting navigation, turning on air conditioner and turning on music. At the same time, the system also supports four-tone independent interaction, and each passenger can control the train independently with voice, with excellent recognition accuracy and command response speed.

In the field of intelligent driving, the media focused on AEB’s emergency braking ability and intelligent driving assistance ability, and conducted a rigorous test of "ACC battle in the snow at night". Finally, Wangwang U8 successfully passed the static fake car test in the snow ACC 60km/h at night, the static fake car test in the backlight ACC 60km/h at night, and the static fake car test in the backlight ACC 40km/h at night, and became the first echelon, which fully confirmed the technical level of its AEB system and intelligent driving system. It is worth mentioning that not long ago, BYD conducted an AEB test by looking up at the U8 test vehicle, and the top speed of successful braking and braking came to 130 km/h. Although the test video showed that this function has not been mass-produced on the car, it has fully demonstrated the leading position of BYD AEB technology.

Judging from the harsh winter test of the media, the strength of U8′ s hard-core products with real endurance, strong control and high safety has been fully verified, and the final test results are quite excellent. Just in the past December, Wangwang U8 Deluxe Edition ranked first in the sales of millions of new energy SUVs in the first complete delivery month with the monthly sales of 1,593 vehicles, which made Wangwang successfully become the first echelon of millions of high-end brands and created history. As a high-end brand built with the ultimate technology, I hope that I have completed the first step of "rushing" and the future can be expected.

Extreme krypton or the fastest listed new force to build a car in history

Business News (Reporter Wang Zhuyu) It has been established for less than three years, and it is expected to become the "fastest IPO in history" brand of high-end pure trams. Recently, Krypton publicly submitted a prospectus to land on the New York Stock Exchange, with the stock code "ZK". At present, Geely Holding Group has 9 listed or planned listed companies, including Krypton, and Li Shufu, the helm of Geely, has ushered in a bumper IPO.

According to public information, Extreme Krypton was established in March 2021 and is a high-end intelligent pure electric vehicle brand hatched by Geely Holding Group. If it is successfully listed before March 2024, it will become the "fastest IPO in history" new energy automobile enterprise. For reference, it took Weilai, Tucki and Ideality, who are also new car-making forces, about 4 years, 6 years and 5 years to go public in the United States respectively. Tesla also spent seven years.

According to the prospectus, apart from producing high-end pure electric vehicles, Extreme Krypton also provides technology-driven solutions and is committed to leading the electrification, intelligence and innovation of the automobile industry. At present, Krypton has released four models, including Krypton 001, Krypton 001FR, Krypton 009 and Krypton X.

The data shows that in 2022, 72,000 vehicles were delivered throughout the year. In the first half of 2023, 43,000 vehicles were delivered, a year-on-year increase of 124.3%. By the end of October 2023, Krypton had delivered more than 170,000 vehicles.

The rapid increase in car sales has led to a significant increase in revenue. In 2022, Krypton achieved revenue of 31.899 billion yuan. In the first half of 2023, the revenue was nearly 21.3 billion yuan, a year-on-year increase of 136%, of which the vehicle sales revenue was 13.175 billion yuan, a year-on-year increase of 148.75%.

In terms of gross profit margin, the gross profit margin of Krypton vehicles reached 12.3% in the first half of this year, up 7.6 percentage points year-on-year. Earlier, An Conghui, CEO of Extreme Smart Technology, revealed that Extreme Smart is already the pure electric brand with the best gross profit level except Tesla. This year, the company’s gross profit margin target is in double digits. Judging from its growth momentum, Krypton is expected to become the first and fastest electric vehicle company to make money except Tesla.

According to the plan, Krypton plans to enter the pure electric vehicle market in Europe and the Robotaxi market in the United States in the future. And this will bring about a corresponding increase in R&D, marketing and other expenses. The data shows that in the first half of 2023, the R&D expenses of Krypton reached 3.19 billion yuan, and the sales, general and administrative expenses were 2.90 billion yuan.

As an important bet of Geely in the field of new energy, it is urgent to improve its "hematopoietic" ability, and listing is bound to be one of the paths of capital blessing. On August 25 this year, the CSRC confirmed the information on overseas listing. According to the filing notice of overseas issuance and listing, Krypton plans to issue no more than 926 million ordinary shares and list them on the New York Stock Exchange.

According to the prospectus, the funds raised by this IPO are mainly used for three purposes: about 45% is used for "developing more advanced pure electric vehicle technology and expanding product portfolio"; About 45% is used for "sales and marketing, expanding service and charging network"; 10% is used for "general purpose of the enterprise, including the working capital requirements to support the company’s business operation and growth".

In recent years, many brands under Geely have rushed to the capital market. At present, there are 9 listed or planned listed companies, including Geely Automobile, Volvo Automobile, Lotus Technology, Polar Star, Yikatong, Extreme Krypton Automobile, Qianjiang Motorcycle, Hanma Technology and Lifan Technology. While Li Shufu, the helm of Geely, ushered in a bumper IPO, it also made Geely Holding Group’s "team battle" ability expand.

Some market analysts believe that the independent listing of Geely’s brands will enable Geely to achieve large-scale operations. As Li Shufu said in his internal speech: "In the end, the number of global automobile industry enterprises will not be too much, and only large-scale enterprises can survive."

It’s really not a little bit that mobile phones are harmful to health.

  How far is it from playing mobile phone every day to illness? Recently, a reporter from qianjiang evening news learned from the hospital that there is a 30-year-old clerk in Hangzhou who deals with computers, keyboards and mice every day, and likes to play with mobile phones during the spare time. As a result, his hands are numb enough to require surgery. Psychologists also warned mobile phone owners that if they keep looking at their mobile phones while shopping, they will spend more money. If you let your mobile phone sleep with you, it will do more harm to your health.

  Keyboard and mobile phone play too much.

  In addition to hand numbness, muscle atrophy will occur.

  Zhou Qi (a pseudonym), 30, keeps her hands on the keyboard at work and keeps brushing her mobile phone at rest. She also has a habit of sleeping on her desk with her hands on her pillow during lunch break. It seems that most people’s living habits have damaged her ulnar nerve. It shows that the right hand is numb and tingling, and it takes a long time to straighten your arm to recover. Even the buttons are awkward, and you can’t even carry chopsticks when eating … … After a series of examinations such as electromyography, Zhou Qi was diagnosed as "cubital tunnel syndrome".

  The ulnar nerve in medicine is what we usually call "numbness". It is one of the three main meridians on the arm. It starts from the cervical vertebra, passes through the elbow joint, sticks to the inside of the arm and goes down all the way to our ring finger and little finger. It is of great significance to our daily life, and the fine movements of our fingers, such as buttoning, holding chopsticks and holding a pen, can not be achieved without the contribution of ulnar nerve.

  Frequent elbow flexion and other actions will cause ulnar nerve compression, leading to "cubital tunnel syndrome", which will affect the function of fingers and palms. When the sensory function of ulnar nerve is affected, there will be symptoms of numbness of fingers or palms, and when its motor function is also affected, there will be phenomena such as weakness of fingers or muscles. If it is affected for a long time, it will easily cause muscle atrophy and even cause serious irreversible consequences.

  Use the keyboard and mouse for a long time, bend your elbows for a long time, or sleep on your desk, etc. Some people have cubital tunnel syndrome due to playing mahjong for several days, and office workers and surgeons are all high-risk groups. In order to completely cure the symptoms, Zhou Qi had to undergo surgery.

  The doctor reminded that to prevent such diseases, one is: rest.

  If you repeat an activity, whether it is typing, using the mouse or anything else, it is recommended to take a short break every 10 to 15 minutes to rest your elbow and wrist. During this period, you can stretch and exercise these two parts.

  Second, keep a good working posture.

  Adjust the height of the seat to keep the forearm as high as the keyboard. When using the keyboard, there should be no feeling of outward expansion and drooping, so that the elbows and wrists are in a relatively relaxed state.

  The third is: always be vigilant. Once there is numbness and discomfort in the finger, and it is a constant and persistent feeling, you must not ignore it easily. You should go to the hospital as soon as possible for professional judgment and exclusion.

  Play mobile phone while walking.

  Shopping is more expensive.

  A new study by American scientists shows that if you play with your mobile phone while shopping, it will not only increase the risk of hitting obstacles, but also make people spend a lot of money unconsciously.

  The research team of Fairfield University asked 231 participants to complete a simulated shopping task. One group of participants restrained themselves from taking out their mobile phones and only paid attention to the goods, while the other group randomly used their mobile phones intermittently for unrelated tasks (such as answering phones, sending and receiving text messages, listening to music, etc.). Both groups of participants used to shop according to a shopping list provided by the researchers, but the results showed that people who used their mobile phones occasionally or constantly in the store made far more unplanned purchases than those who concentrated on shopping.

  The researchers pointed out that when shopping, people may forget what goods they need most when they are distracted, but they will be attracted by the dazzling array of other goods in the store and take them into their pockets without thinking. Even if you only use your mobile phone occasionally during shopping, it will have this effect, which will lead to additional expenses. Therefore, we should concentrate on saving money when shopping.

  Wang Yiquan, an expert in early intervention of psychological problems in Hangzhou No.7 Hospital, said: "From the perspective of behavior patterns, those who rely heavily on mobile phones have poor self-control ability, and they are easily influenced by external information such as price reduction and new product listing when shopping, resulting in more impulsive consumption. From the analysis of emotional influence, the information from the mobile phone will affect the mood of shoppers, and these emotions may stimulate impulsive consumption whether positive or negative. Seeing good news, buy something to reward yourself or your family; When you see bad news, you should buy something to comfort yourself and decompress. For example, people often joke that ‘ Bao ’ Treating all diseases is the most vivid explanation of the influence of emotions on shopping. "

  We have to admit that consumption is indeed a good way to vent and quickly adjust emotions, but only if it is moderate. If it is inappropriate or even unreasonable consumption beyond one’s own ability to pay, one must be alert to whether there are psychological problems.

  In fact, in life, it is easy to understand the difference between men and women’s shopping habits. For most men, shopping is a kind of "torture". They often think about where to buy something, go straight to the destination and buy it, and then leave. They rarely pay attention to what other stores are selling along the way, and naturally they will not have unplanned consumption. Women tend to take shopping as a kind of "leisure", walk around, shop around, stop and watch more, and the temptation is more likely to lead to many unplanned consumption.

  Sleeping with your mobile phone is harmful to your eyes.

  Playing mobile phone for a long time at night often leads to sore eyes, sharp drop in vision, deepening myopia, and even dry eye. Once, because of playing mobile phone games for a long time, the function of meibomian gland was worse than that of the elderly.

  Everyone’s two eyes have a dominant eye and a non-dominant eye. Under normal circumstances, under the control of the brain, the eyes of both eyes are even, but after lying on the side, one eye has to shoulder a heavier eye task. Over time, if the balance is broken, the vision will be inconsistent between the left and right eyes.

  Sleeping with mobile phone is harmful to cervical health

  "Cervical arch inversion" is the most common pathological basis of cervical diseases. High pillow can make the head bend forward and increase the stress of the lower cervical vertebra, which may accelerate the degeneration of cervical vertebra. However, bad living habits such as lying on a high back and watching TV, surfing the Internet for a long time, lying down and playing with a mobile phone, and pulling the cervical vertebra for a long time will also lead to the curve lordosis decreasing, straightening and even bending back.

  Sleeping with mobile phone affects sleep quality.

  Adequate sleep is a necessary guarantee for a healthy life. When playing mobile phone, the production of melatonin (secreted by pituitary gland, which directly affects the quality of sleep) will be reduced, which will lead to less sleep and even inability to sleep. I believe those who play mobile phones until midnight or even later have a profound experience — — I’m not sleepy at all. I don’t want to sleep.

  Sleeping with mobile phones affects family harmony.

  Young people, once they have cell phone sleepiness, are not in a hurry to find a partner. They think that cell phones are so fun and have everything in them. Why do they need to find a partner? Parents look at the older single children, but they really hate the dead mobile phone. After three days, they cursed, "I know how to play mobile phones every day. Everyone else has grandchildren, so you will give me a mobile phone?"

In-depth experience BYD Yunqi family redefines body control with technology.

  As the world’s first exclusive intelligent body control system for new energy, Yunqi has been receiving much attention since its release in April. Nowadays, the cloud system has been gradually installed on various models of BYD, allowing more users to experience the power of cloud technology. The cloud system was developed by BYD, which made BYD the first enterprise to master the 3-way 6-degree-of-freedom body control technology. BYD’s first product matrix of Yunqi, which currently includes Yunqi -C, Yunqi -A, Yunqi -P and other products, can greatly enhance our driving experience in many aspects such as comfort, handling, safety and off-road.


  It is luxurious to carry, and Yunnian -C creates a new experience of driving and leaping forward.

  Yunqi -C intelligent damping body control system can realize rapid and continuous variable adjustment of damping through thousands of signal inputs per second. At the same time, with the cloud algorithm, the optimal damping control scheme can be output in real time to meet the needs of users in different scenarios.


  During the test drive of Han DM-p Ares Edition, it can be clearly felt that Yunqi -C makes the chassis "hard" by adjusting the damping, which provides greater support for the body and makes the driving and handling feeling of the whole vehicle more stable. At the same time, in the face of bumpy road conditions such as speed bumps and gravel roads, Yunxiao -C can make the chassis "soft", effectively buffering the impact of the road surface on the whole vehicle and greatly improving driving comfort. Whether it is a test of the sense of control or an experience of comfort, Yunqi -C’s performance is amazing.


  Exercise and comfort are perfectly compatible, and Yunnian -A sets a new benchmark for luxury and comfort.

  Yunqi -A intelligent air body control system can give consideration to both driving maneuverability and comfort, and at the same time, output precise control strategies through Yunqi Intelligent Computing Center to realize dynamic adjustment of vehicle stiffness, height and damping, and bring more detailed and diversified control to the whole vehicle.


  In the process of experiencing Tengshi N7 equipped with the standard version of Yunqi -A, the most intuitive feeling is convenience, comfort and luxury. It can realize the functions of welcoming guests and taking things conveniently by adjusting the height, which makes it more convenient for us to get on and off the bus and move things in our daily life. In case of sudden acceleration or sudden braking during driving, the iCCT intelligent comfort control technology carried by Yunqi -A can achieve stronger anti-pitching ability, effectively restrain the vehicle from raising its head and nodding, and greatly reduce the discomfort of the passengers.


  However, when faced with the scene of high-speed steering such as Panshan Highway, Yunqi -A can not only restrain the roll of the car body, but also integrate suspension, braking and driving through iCVC intelligent vector control technology. Even in the face of the difficult continuous mountain curve, it can easily enter and exit the curve with a very steady posture, and it is handy to control. With the help of iADC intelligent drift control system, drift is no longer the exclusive skill of "high-level players", and even ordinary people can enjoy drift with one click. Yunqi -A has achieved a perfect integration between luxury driving and interesting handling, and the overall experience is impressive.

  Let cross-country have no threshold, and Yunqi -P brings subversive experience.

  Yunqi -P intelligent hydraulic body control system integrates three core technologies of machinery, hydraulics and electronic control to fully meet the off-road needs of users. Yunqi -P can adjust the height, damping and stiffness. When driving U8 in mountain road, you can obviously feel that the road vibration is filtered completely, and the support is also in place in the corner. It is not like the traditional hard-core SUV, and there will be no many small vibrations. For Yunnian -P, this kind of comfort experience on unpaved pavement is unprecedented.


  Looking up at U8 and Equation Leopard 5 under the blessing of Yunnian -P can not only realize the long suspension adjustment stroke, but also have the "hidden function" ultra-high and ultra-low mode. Therefore, even a behemoth like U8 can "hold the bottom" in extreme off-road conditions and "touch the head" in the urban restricted highland basement. At the same time, Yunqi -P with strong off-road performance has also added intelligent genes. The four-wheel linkage function can intelligently distribute the oil pressure through the central control cylinder, so that the four wheels can keep touching the ground at all times, which greatly improves the off-road passability. When parking in the wild, you can also keep the vehicle absolutely level by camping leveling function, so that the rest in the car will no longer be disturbed by terrain. It can be said that Yunqi -P greatly lowered the cross-country threshold, allowing Xiaobai to cross-country easily, bringing unprecedented experience to drivers and passengers.


  BYD leads the industry with cloud technology.

  Most importantly, Yunqi started from the systematic control of the vertical direction of the whole vehicle, and realized the safety of the whole vehicle. On the one hand, it can greatly reduce the risk of vehicle rollover and increase the safety of passengers by restraining the change of body posture; On the other hand, the cloud system can adjust the posture of the car body at any time through 3-to-6-degree-of-freedom fusion control under complex road conditions such as snow, mud and water. The cloud chariot system can not only effectively protect the safety of passengers, but also effectively protect the car body, and truly realize the dual protection of people and cars.

  In the future, BYD will also launch Yunqi -X, which represents the highest level of the global body control system. At the press conference, BYD had already demonstrated the power of Yunqi -X by looking up to U9 for dancing and three-wheeled driving. Recently, Porsche Active Ride, the new hydraulic active suspension system of Porsche’s third generation Paramera, has also earned enough attention in the form of "dancing". Different from Porsche, BYD Yunqi -X is more advanced in system design ideas and realizable functions through innovative new energy architecture. This also proves that BYD has been at the forefront of the industry in the field of body control, and will continue to lead the development direction of the industry with forward-looking technical layout.


  Through the experience of the whole family of Yunqi, we can clearly feel the overall improvement of the comfort, handling and off-road performance of Yunqi. There is no doubt that Yunqi is a super technology with the ultimate experience and safety. As BYD’s cutting-edge black technology, Yunqi’s birth not only fills the gap in the field of domestic body control technology, but also enables more domestic users to experience the high-end driving and control experience, and further realizes the technological transcendence of established western car companies and promotes the world’s automobile technology to a new height.

250,000 ~ 320,000 yuan, Huawei’s intelligent selection of AITO asked M5 officially released: the design concept of one million luxury cars, performance, endurance and environmental protection. …

On December 23rd, Chongqing Jin Kang Sailis announced that it had jointly launched a high-end smart car brand AITO (Chinese name: Aotu), which is a new high-end new energy brand that Huawei has chosen new products and cooperated with car companies. slogan is "A journey of thousands of miles begins with AITO"!

poster;playbill

At today’s new product launch conference of Huawei in winter, AITO’s first model, AITO Wenjie M5, was officially launched, with a mid-to-high-end positioning, belonging to an intelligent luxury electric drive SUV (medium-sized), which was built by major teams such as Huawei’s consumer business, including system software, industrial design, engineering technology, ecology, etc., with high autonomy.

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In addition, HUAWEI has specially provided Huawei’s household charging piles for new cars, which are genuine Huawei car accessories to help solve the anxiety of users.

The IT House learned that "Huawei only makes parts and does not build cars, but helps enterprises build good cars".

Yu Chengdong said that this model is far superior to other brands in terms of performance, handling and intelligent experience.

Huawei also brought its simple and ultimate industrial design concept to this car. The exterior is luxurious and compact, and the interior is spacious and comfortable, which not only allows everyone to enjoy the convenience of parking and turning around easily in the city, but also allows the main driver and passengers to have a comfortable experience even during the long journey.

With the help of the industrial concept of Huawei team, this car has achieved a simple and extreme design. First, it is equipped with an intelligent cockpit. The AITO M5 can seamlessly flow with other intelligent terminals, completely breaking through the barriers between "people, cars and homes".

poster;playbill

In terms of software, the M5 interface of AITO Interface provides advanced sense and intelligent functions, which "surpasses all models and car enterprises", such as L2+intelligent driving assistance, HarmonyOS intelligent split screen, one-button flow, NFC Bluetooth sensorless car key of Huawei watch, 3D face recognition, automatic login to Huawei account, automatic switching of driving information, schedule, real-time updating of car navigation map, intelligent sound source perception in multi-tone area, offline voice assistant, real-time detection of fatigue state by computational vision, etc.

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Huawei said that with powerful computing power and operating system, through continuous AI learning optimization and OTA upgrade, HarmonyOS Auto can meet consumers’ demand for intelligent, scene-based and personalized experience upgrade.

IT House understands that AITO Wenjie M5 has six paint colors: ceramic white, pine frost green, ice crystal gray, gold-plated black, mi navy blue and azure blue, and three interior colors: ivory white, extreme night black and agate brown, which can be freely matched.

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According to Yu Chengdong, Huawei designed it according to the quality and interior requirements of millions of luxury cars, which exceeded the driving sense of 500-100 million yuan. The interior space was comparable to that of a large SUV, and the cockpit was surrounded in one piece, which perfectly interpreted the experience of "advanced feeling", "simplicity" and "immersion".

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In terms of power, AITO Wujie M5 adopts front double wishbone independent suspension (anti-roll), rear multi-link independent suspension (stable), all-aluminum chassis (weight -30%), and is equipped with Huawei’s own DriveOne pure electric drive range-extending platform, which has fast acceleration, long battery life and can be powered by electricity and oil.

It is equipped with 1.5T four-cylinder range extender 3.0, asynchronous AC motor and permanent magnet synchronous motor. The peak power of intelligent four-wheel drive flagship version is 365kW(675N?m), and the performance version of four-wheel drive is 315kW. Its performance is superior, and its endurance exceeds that of Porsche, BMW X3, Mercedes-Benz GLC, Audi Q5L, Tesla Model Y and many other luxury cars, with the highest compression ratio of 15:1, ultra-high thermal efficiency of 41% and 3.

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According to Yu Chengdong, this model also has extreme cornering performance, which is stronger than McLaren. In terms of acceleration, it can also achieve acceleration of 4.4 seconds at zero speed and 1.9 seconds at 0-50km/h, and its performance can crush many fuel vehicles and surpass many pure trams.

Advanced precision oil cooling technology is also adopted in AITO Interface M5, which reduces the average peak temperature of winding by 30℃ and the peak temperature of magnetic steel by 15℃.

This model can store 40 kWh of electricity, and has a matching "Huawei Household Charging Pile", which supports fast charging (45 minutes can make the power from 20% to 80%, and 5 hours of slow charging can make the power from 20% to 80%), and of course it can also generate electricity from gasoline (56L fuel tank), and it can also output 3500W(220V) AC power to the outside world. Super fast charging charging charging charging treasure, four-wheel drive flagship version 110.

It is reported that the interior car of AITO’s M5 is a 15.9-inch 2K HDR screen, with 90% screen ratio, 128-color RGB atmosphere lights and seamless panoramic canopy.

In addition, this model also has built-in Huawei Sound’s top luxury audio system and a car audio with a peak of 1200 watts. It is worth mentioning that Huawei also has a high-quality cockpit music experience, providing a 10-million-level music library and a high-quality music area for Huawei music, and supporting the playback of lossless music with 5.1 channels and 7.1 channels.

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In other aspects, AITO Wujie M5 comes with its own fragrance system, which claims to have the fastest charging in the car, 66W wired fast charging and 40W wireless fast charging, with five charging interfaces of 1A4C, as well as the advanced crystal diamond handle, the co-pilot’s "Queen’s fill lens", center speaker, 19-unit vocal design, ventilated heating massage seat, Napa leather, HUD head-up display function and so on.

Finally, AITO M5 also provides Huawei Card Owner’s Courtesy Edition, covering the whole life cycle from car purchase to car use, providing preferential installment service and rich owner’s rights and interests. With the owner card of Huawei Card, you can enjoy the owner’s rights and services. In Huawei wallet App, car owners can quickly apply for cards, handle car staging, enjoy cash back and driver accident insurance on the whole line, and create a variety of smart car scenes.

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Yi tu zhi

Jiaxing Tang new energy price cuts hit! The reserve price is 179,800 yuan, which is a great benefit today.

The model is being promoted in Jiaxing, with a maximum discount of 80,000 yuan! The minimum starting price is 179,800 yuan. If you are interested in this model, you can click "Check the car price" in the quotation form to get a higher discount. As a plug-in hybrid vehicle, Tangxin Energy not only has excellent fuel economy and environmental protection performance, but also has excellent driving performance and comfort, so it is a popular choice in the new energy vehicle market. Now is a good time to buy a car. Come to Jiaxing and enjoy the discount of Tang New Energy!

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Tang New Energy is a luxury SUV with an atmospheric and steady overall style. Its front face design adopts BYD’s family-style "dragon face" design language, and the air intake grille is decorated with large chrome, which gives people a strong visual impact. The body lines are smooth and concise, and the overall shape is fashionable and dynamic. In addition, Tang New Energy also adopts LED headlight group, which not only improves the lighting effect, but also increases the recognition of vehicles. The side of the car body adopts a smooth waistline, which runs from the front of the car to the rear of the car, increasing the dynamics of the car body. Generally speaking, the design of Tang New Energy not only embodies the sense of luxury, but also does not lose the sense of fashion. It is an excellent SUV model.

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As a medium-sized SUV, BYD Tang New Energy has performed well in body size, with a body length of 4870mm, a width of 1950mm, a height of 1725mm and a wheelbase of 2820mm, providing passengers with spacious interior space. The front and rear wheel tracks are 1650mm and 1630mm respectively, which makes the vehicle more stable when driving. In tyre size, the former tyre size is 255/50 R20, and the latter tyre size is also 255/50 R20. This large-size tire not only improves the handling performance of the vehicle, but also makes the vehicle more visually impactful. The side lines of the car are smooth, and the overall shape is fashionable and atmospheric, showing the luxury temperament of BYD Tang New Energy.

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The interior design of Tang New Energy Car Series is fashionable and luxurious, and a large number of soft materials and leather wraps are used to improve the texture and comfort of the whole car. The steering wheel is made of leather material, which can be manually adjusted up and down+back and forth, so that the driver can find the most comfortable driving posture. The central control screen size is 15.6 inches, which supports voice recognition control system, including multimedia, navigation, telephone, air conditioning and skylight, and is easy to operate. The front and rear rows are equipped with USB/Type-C interfaces, which are convenient for charging and connecting devices. The front row also has mobile phone wireless charging function, which makes drivers more convenient. The seat is made of imitation leather. The main seat supports front and rear adjustment, backrest adjustment and height adjustment (4 directions), and the auxiliary seat also supports front and rear adjustment and backrest adjustment. The front seats also have heating and ventilation functions to provide a more comfortable driving experience. The rear seats can be tilted in proportion, which increases the practicability of the vehicle. In a word, the interior design of Tang New Energy Car Series is exquisite and rich in configuration, which provides a comfortable and convenient experience for drivers and passengers.

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Tang New Energy is equipped with a 1.5T 139 L4 engine with a maximum power of 102 kW and a maximum torque of 231N m.. Equipped with E-CVT continuously variable transmission, it makes the shift smoother and provides a more comfortable driving experience. This engine has excellent power performance and efficient fuel economy, which can meet the needs of daily driving and long-distance travel. Whether it is urban roads or expressways, Tangxin Energy can provide sufficient power support, so that drivers can feel strong power output and stable driving performance.

In terms of the exterior design of Tang New Energy, we can see that the evaluation is very pertinent. The front face adopts a family-style design, the lines are tough, full of strength, the design of the tail penetrating taillights is simple and generous, and the wheels are very beautiful. These details make Tang New Energy present an atmospheric and tough image in appearance, which leaves a deep impression on people. At the same time, as a new energy vehicle, Tangxin Energy also has outstanding performance in environmental protection, energy saving and power. It can be said that Tang New Energy is a car with both value and strength, which is a very good choice for consumers who pursue quality life.